Tag: Hippocampus

How does the brain translate experiences into structured knowledge that allows us to navigate to achieve goals?

Corey Fernandez, Jiefeng Jiang, Shao-Fang Wang, Hannah Choi, Anthony D Wagner. Representational integration and differentiation in the human hippocampus following goal-directed navigation. bioRxiv 2022.04.12.488078; doi: https://doi.org/10.1101/2022.04.12.488078

Abstract
“As we learn, dynamic memory processes build structured knowledge across our experiences. …

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How do hippocampal neurons contribute to memorizing and utilizing information acquired through social observations and interactions?

Mou, Xiang, Abhishekh Pokhrel, Prakul Suresh, and Daoyun Ji. “Observational learning promotes hippocampal remote awake replay toward future reward locations.” Neuron, Volume 110, Issue 5, 2 March 2022, Pages 891-902.e7

Summary
The neural circuit mechanisms underlying observational

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Whether place cells encode the angular and linear position as well as motion direction of a simple stimulus, regardless of self-motion, memory or reward?

Chinmay S. Purandare, Shonali Dhingra, Rodrigo Rios, Cliff Vuong, Thuc To, Ayaka Hachisuka, Krishna Choudhary & Mayank R. Mehta. Moving bar of light evokes vectorial spatial selectivity in the immobile rat hippocampus. Nature (2022). https://doi.org/10.1038/s41586-022-04404-x

Abstract
“Visual cortical neurons …

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What is the principle of the functional circuit interactions between LEC and the hippocampus?

Olesia M Bilash, Spyridon Chavlis, Panayiota Poirazi, Jayeeta Basu. Lateral entorhinal cortex inputs modulate hippocampal dendritic excitability by recruiting a local disinhibitory microcircuit. bioRxiv 2022.01.13.476247; doi: https://doi.org/10.1101/2022.01.13.476247

Abstract
The lateral entorhinal cortex (LEC) provides information about multi-sensory environmental

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How does the hippocampus represent 3D space in past, present and future?

Nicholas M. Dotson and Michael M. Yartsev. Nonlocal spatiotemporal representation in the hippocampus of freely flying bats. SCIENCE 09 JUL 2021 : 242-247

“The neural code for 3D map–based navigation in area CA1 of bats forms a continuum through …

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What is the neural code for very large spaces?

Eliav T, Maimon SR, Aljadeff J, Tsodyks M, Ginosar G, Las L & Ulanovsky N, Multiscale representation of very large environments in the hippocampus of flying bats, Science 372, eabg4020 (2021). PDF | News&Views: Wood & Dudchenko

Abstract
“Hippocampal …

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How do time cells in the human hippocampus and entorhinal cortex support episodic memory?

Gray Umbach, Pranish Kantak, Joshua Jacobs, Michael Kahana, Brad E. Pfeiffer, Michael Sperling, Bradley Lega. Time cells in the human hippocampus and entorhinal cortex support episodic memory. Proceedings of the National Academy of Sciences Nov 2020, 117 (45) 28463-28474; …

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