Category: Cognitive Map

How the medial entorhinal cortex develops during learning and influences memory?

Malone, T.J., Tien, NW., Ma, Y. et al. A consistent map in the medial entorhinal cortex supports spatial memoryNat Commun 15, 1457 (2024). https://doi.org/10.1038/s41467-024-45853-4

Abstract
The medial entorhinal cortex (MEC) is hypothesized to function as a

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How place cells use environmental cues to resolve the ambiguity of arotationally symmetric environment?

Cheng, Han Yin, Dorothy W. Overington, and Kate J. Jeffery. “A configural context signal simultaneously but separably drives positioning and orientation of hippocampal place fields.” Hippocampus 34.2 (2024): 73-87.

Abstract
Effective self-localization requires that the brain can

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Whether animals can intentionally control their hippocampal activity according to their model of the world

Chongxi Lai et al., Volitional activation of remote place representations with a hippocampal brain–machine interface. Science382,566-573(2023).DOI:10.1126/science.adh5206

Editor’s summary

“The hippocampus holds a model of the environment that can be mentally traversed during recall or simulation. …

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How hippocampal activity relates to spatial behaviour in dynamic and ethologically relevant group settings?

Forli, A., Yartsev, M.M. Hippocampal representation during collective spatial behaviour in batsNature (2023). https://doi.org/10.1038/s41586-023-06478-7

Abstract
Social animals live and move through spaces shaped by the presence, motion and sensory cues of multiple other individuals1,2,3,4,5,6. Neural activity

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How the cortical circuits integrate vestibular and visual cues for navigation, visual processing, and perception?

Sepiedeh Keshavarzi, Mateo Velez-Fort, and Troy W. Margrie. Cortical Integration of Vestibular and Visual Cues for Navigation, Visual Processing, and Perception. Annual Review of Neuroscience, Vol. 46:301-320, July 2023. https://doi.org/10.1146/annurev-neuro-120722-100503

Abstract
“Despite increasing evidence of its involvement in several …

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How the hippocampus supports real-world navigation in humans?

Kathryn N. Graves, Ariadne Letrou, Tyler E. Gray, Imran H. Quraishi, Nicholas B. Turk-Browne. Hippocampal Codes for Real-World Human Navigation. bioRxiv 2023.06.22.545396; doi: https://doi.org/10.1101/2023.06.22.545396

Abstract
“As animals move through the world, the hippocampus represents their location, direction, and speed

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How hippocampal CA1 neurons encode both world-centered spatial information and animals’ location relative to the local landmarks, with a common directional input presumably provided by the head direction cell system?

Yue-Qing Zhou, Vyash Puliyadi, Xiaojing Chen, Joonhee Leo Lee, Lan-Yuan Zhang, James J. Knierim. Conjunctive vector coding and place coding in hippocampus share a common directional signal. bioRxiv 2023.06.02.543340; doi: https://doi.org/10.1101/2023.06.02.543340

Abstract
Vector coding is becoming increasingly understood

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