How different sensory streams are integrated to drive spatial navigation in the brain?

Currier, Timothy A., and Katherine I. Nagel. “Multisensory control of navigation in the fruit fly.” Current Opinion in Neurobiology 64 (2020): 10-16.

Spatial navigation is influenced by cues from nearly every sensory modality and thus provides an excellent model for understanding how different sensory streams are integrated to drive behavior. Here we review recent work on multisensory control of navigation in the model organism Drosophila melanogaster, which allows for detailed circuit dissection. We identify four modes of integration that have been described in the literature—suppression, gating, summation, and association—and describe regions of the larval and adult brain that have been implicated in sensory integration. Finally we discuss what circuit architectures might support these different forms of integration. We argue that Drosophila is an excellent model to discover these circuit and biophysical motifs.”

Currier, Timothy A., and Katherine I. Nagel. “Multisensory control of navigation in the fruit fly.” Current Opinion in Neurobiology 64 (2020): 10-16.